Amyloid diseases: abnormal protein aggregation in neurodegeneration.
作者信息
Koo E H, Lansbury P T, Kelly J W
机构信息
Department of Neurosciences, University of California at San Diego, La Jolla, CA 92093, USA.
出版信息
Proc Natl Acad Sci U S A. 1999 Aug 31;96(18):9989-90. doi: 10.1073/pnas.96.18.9989.
Abstract
摘要
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本文引用的文献
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Assembly of A beta amyloid protofibrils: an in vitro model for a possible early event in Alzheimer's disease.β淀粉样蛋白原纤维的组装：阿尔茨海默病可能早期事件的体外模型
Biochemistry. 1999 Jul 13;38(28):8972-80. doi: 10.1021/bi9904149.
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Fatal attractions: abnormal protein aggregation and neuron death in Parkinson's disease and Lewy body dementia.致命诱惑：帕金森病和路易体痴呆中的异常蛋白质聚集与神经元死亡
Cell Death Differ. 1998 Oct;5(10):832-7. doi: 10.1038/sj.cdd.4400432.
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Evolution of amyloid: what normal protein folding may tell us about fibrillogenesis and disease.淀粉样蛋白的演变：正常蛋白质折叠能为我们揭示有关纤维形成及疾病的哪些信息。
Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3342-4. doi: 10.1073/pnas.96.7.3342.
4
Characterization of the transthyretin acid denaturation pathways by analytical ultracentrifugation: implications for wild-type, V30M, and L55P amyloid fibril formation.通过分析超速离心法对转甲状腺素蛋白酸变性途径的表征：对野生型、V30M和L55P淀粉样原纤维形成的影响
Biochemistry. 1998 Dec 22;37(51):17851-64. doi: 10.1021/bi981876+.
5
Traumatic brain injury increases beta-amyloid peptide 1-42 in cerebrospinal fluid.创伤性脑损伤会增加脑脊液中β-淀粉样肽1-42的含量。
J Neurochem. 1998 Dec;71(6):2505-9. doi: 10.1046/j.1471-4159.1998.71062505.x.
6
Inhibiting transthyretin conformational changes that lead to amyloid fibril formation.抑制导致淀粉样纤维形成的转甲状腺素蛋白构象变化。
Proc Natl Acad Sci U S A. 1998 Oct 27;95(22):12956-60. doi: 10.1073/pnas.95.22.12956.
7
Discovering transthyretin amyloid fibril inhibitors by limited screening.通过有限筛选发现转甲状腺素蛋白淀粉样纤维抑制剂。
Bioorg Med Chem. 1998 Aug;6(8):1389-401. doi: 10.1016/s0968-0896(98)00130-8.
8
Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins.源自β淀粉样蛋白1-42的可扩散、非纤维状配体是强效中枢神经系统神经毒素。
Proc Natl Acad Sci U S A. 1998 May 26;95(11):6448-53. doi: 10.1073/pnas.95.11.6448.
9
The alternative conformations of amyloidogenic proteins and their multi-step assembly pathways.淀粉样蛋白的不同构象及其多步组装途径。
Curr Opin Struct Biol. 1998 Feb;8(1):101-6. doi: 10.1016/s0959-440x(98)80016-x.
10
Atomic force microscopic imaging of seeded fibril formation and fibril branching by the Alzheimer's disease amyloid-beta protein.阿尔茨海默病β淀粉样蛋白引发的原纤维形成及原纤维分支的原子力显微镜成像
Chem Biol. 1997 Dec;4(12):951-9. doi: 10.1016/s1074-5521(97)90303-3.
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