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西澳大利亚一家体外受精诊所内接近法定储存期限的冷冻人类胚胎的命运。

The fate of cryopreserved human embryos approaching their legal limit of storage within a West Australian in-vitro fertilization clinic.

作者信息

Darlington N, Matson P

机构信息

Concept Fertility Centre, King Edward Memorial Hospital, Bagot Road, Subiaco, Western Australia 6008.

出版信息

Hum Reprod. 1999 Sep;14(9):2343-4. doi: 10.1093/humrep/14.9.2343.

Abstract

Human embryos can only be stored in the first instance for 3 years in Western Australia, according to the West Australian Reproductive Technology Act. Thereafter, an application must be made to the local regulatory body, the Reproductive Technology Council, for an extension. Of the 650 batches of embryos frozen between 8 April 1993 and 31 October 1995, 170 (26.2%) batches were still in storage after 2.5 years. A reminding letter was sent at this time to the couples to whom the embryos belonged, i.e. 6 months before the expiry of the initial storage period, asking for clarification of what was to be done with the embryos. A large proportion of patients (64.7%) chose to either extend the storage period or thaw and transfer the embryos. Curiously, more batches of embryos were discarded (18.8%) than donated to other couples (5.9%). Contact with the patients was lost in a small but significant proportion of cases; more of these had been unsuccessful in their treatment (20.4%) than had achieved a pregnancy (4.3%).

摘要

根据西澳大利亚生殖技术法案,人类胚胎在西澳大利亚最初只能储存3年。此后,必须向当地监管机构生殖技术委员会申请延期。在1993年4月8日至1995年10月31日期间冷冻的650批胚胎中,2.5年后仍有170批(26.2%)在储存中。此时向胚胎所属的夫妇发出了提醒信,即在初始储存期到期前6个月,询问如何处理这些胚胎。很大一部分患者(64.7%)选择延长储存期或解冻并移植胚胎。奇怪的是,被丢弃的胚胎批次(18.8%)比捐赠给其他夫妇的批次(5.9%)更多。在一小部分但数量可观的案例中与患者失去了联系;这些案例中治疗未成功的比例(20.4%)高于成功怀孕的比例(4.3%)。

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