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子宫峡部收缩与胚胎移植:使用子宫探针安全吗?

Junctional zone contractions and embryo transfer: is it safe to use a tenaculum?

作者信息

Lesny P, Killick S R, Robinson J, Raven G, Maguiness S D

机构信息

Academic Department of Obstetrics and Gynaecology, University of Hull, UK.

出版信息

Hum Reprod. 1999 Sep;14(9):2367-70. doi: 10.1093/humrep/14.9.2367.

DOI:10.1093/humrep/14.9.2367
PMID:10469712
Abstract

Applying a tenaculum to the cervix is a common practice when the correction of uterine position prior to embryo transfer is required. Our study was designed to assess junctional zone contractility before and after this procedure in 20 patients at the time of mock embryo transfer (mid-luteal phase, at commencement of down-regulation). Real-time transvaginal ultrasound and computer technology was used to evaluate the contraction pattern and frequency. When a tenaculum was applied, the total number of contractions, the number of cervico-fundal, random and opposing contractions all increased significantly (P values 0.0003, 0.005, 0. 001 and 0.007 respectively). Eleven women displayed cervico-fundal contractions, prominent opposing and random contractions were observed in all 20 patients and four patients generated fundo-cervical waves not seen in any case before stimulation with the instrument. In conclusion, manipulation with a tenaculum in the cervical area stimulates junctional zone contractions and is best avoided at the time of embryo transfer.

摘要

在胚胎移植前需要矫正子宫位置时,用宫颈钳钳夹宫颈是一种常见的操作。我们的研究旨在评估20例患者在模拟胚胎移植时(黄体中期,降调节开始时)进行该操作前后的交界区收缩性。采用实时经阴道超声和计算机技术评估收缩模式和频率。当使用宫颈钳时,总收缩次数、宫颈-宫底、随机和反向收缩次数均显著增加(P值分别为0.0003、0.005、0.001和0.007)。11名女性出现宫颈-宫底收缩,所有20例患者均观察到明显的反向和随机收缩,4例患者产生了在用该器械刺激前任何病例中均未见过的宫底-宫颈波。总之,在宫颈区域使用宫颈钳进行操作会刺激交界区收缩,在胚胎移植时最好避免。

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Junctional zone contractions and embryo transfer: is it safe to use a tenaculum?子宫峡部收缩与胚胎移植:使用子宫探针安全吗?
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