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GATA-2在发育中的禽后脑的表达。

Expression of GATA-2 in the developing avian rhombencephalon.

作者信息

Bell E, Lumsden A, Graham A

机构信息

Department of Developmental Neurobiology, Kings College London, UK.

出版信息

Mech Dev. 1999 Jun;84(1-2):173-6. doi: 10.1016/s0925-4773(99)00070-2.

Abstract

Here we describe the expression pattern of GATA-2 in the developing chick hindbrain. We found that during the early period of neurogenesis this gene specifically labels a particular neuronal subtype, the contralateral vestibular-acoustic neurons of rhombomere 4, and that expression of this gene in these cells is transient. We also found that GATA-2 labels a broader territory of the ventral neural tube at later stages. As well as this hindbrain expression, we also describe expression of GATA-2 in the otic vesicle, oculomotor nucleus, third nerve and metanephros.

摘要

在此,我们描述了GATA-2在发育中的鸡胚后脑的表达模式。我们发现,在神经发生早期,该基因特异性标记一种特定的神经元亚型,即菱脑节4的对侧前庭-听神经元,并且该基因在这些细胞中的表达是短暂的。我们还发现,GATA-2在后期标记了腹侧神经管更广泛的区域。除了在后脑的这种表达外,我们还描述了GATA-2在耳泡、动眼神经核、第三神经和后肾中的表达。

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