Ferreira I H, de Almeida C E, Marre D, Marechal M H, Bridier A, Chavaudra J
Service de Physique, Institut Gustave-Roussy, Villejuif, France.
Phys Med Biol. 1999 Aug;44(8):1897-904. doi: 10.1088/0031-9155/44/8/304.
As in the method for the calibration of 192Ir high-dose-rate (HDR) brachytherapy sources, the ionization chamber wall correction factor A(w), is needed for 192Ir and 60Co gamma rays and 250 kV x-rays. This factor takes into account the variation in chamber response due to the attenuation of the photon beam in the chamber wall and build-up cap and the contribution of scattered photons. Monte Carlo calculations were performed using the EGS4 code system with the PRESTA algorithm, to calculate the A(w) factor for 51 commercial ionization chambers and build-up caps exposed to the typical energy spectrum of 192Ir and 60Co gamma rays and 250 kV x-rays. The calculated A(w) correction factors for 192Ir and 60Co sources and 250 kV x-rays agree very well to within 0.1% with published experimental data (the statistical uncertainty is less than 0.1% of the calculated correction factor value). For the 192Ir sources, A(w) varies from 0.973 to 0.993 and for the 250 kV x-rays the minimum value of A(w) for all chambers studied is 0.983. The calculated A(w) correction factors can be used to calculate the air kerma calibration factor of HDR brachytherapy sources, when interpolative methods are considered, contributing to the reduction in the overall uncertainties in the calibration procedure.
如同校准192Ir高剂量率(HDR)近距离治疗源的方法一样,对于192Ir和60Co伽马射线以及250 kV X射线,需要电离室壁修正因子A(w)。该因子考虑了光子束在室壁和积累帽中的衰减以及散射光子的贡献所导致的电离室响应变化。使用带有PRESTA算法的EGS4代码系统进行蒙特卡罗计算,以计算51个商业电离室和积累帽在暴露于192Ir和60Co伽马射线以及250 kV X射线的典型能谱时的A(w)因子。计算得到的192Ir和60Co源以及250 kV X射线的A(w)修正因子与已发表的实验数据在0.1%范围内非常吻合(统计不确定度小于计算得到的修正因子值的0.1%)。对于192Ir源,A(w)在0.973至0.993之间变化,对于250 kV X射线,所有研究的电离室的A(w)最小值为0.983。当考虑插值方法时,计算得到的A(w)修正因子可用于计算HDR近距离治疗源的空气比释动能校准因子,有助于降低校准过程中的总体不确定度。