Relative effects of graft copolymer and polyamines on triplex stabilization under physiological conditions.
作者信息
Ferdous A, Watanabe H, Akaike T, Maruyama A
机构信息
Department of Biomolecular Engineering, Tokyo Institute of Technology, Yokohama, Japan.
出版信息
Nucleosides Nucleotides. 1999 Jun-Jul;18(6-7):1651-3. doi: 10.1080/07328319908044811.
PMID:10474241
Abstract
Triplex-stabilizing effect of a graft copolymer under physiologically relevant conditions has been evaluated and compared with other polyamines. Here we show that the graft copolymer significantly stabilizes triplex DNAs with amazingly higher efficacy than that of physiological concentrations of spermine and spermidine.
摘要
Zotero 插件