Murata K, Tamai S, Inada Y, Fukui A, Miyamoto S
Department of Orthopaedic Surgery, Nara Medical University, Japan.
Br J Plast Surg. 1999 Apr;52(3):223-9. doi: 10.1054/bjps.1997.3039.
In this paper, we evaluated experimentally the feasibility of transferring a pedicled venous flap with perivenous areolar tissue into an ectopic site and investigated the role of each vein, the perivenous areolar tissue and nerve in the viability of pedicled venous flaps. Three groups of flaps were created using a rabbit-ear model: Group 1 (n = 11), containing perivenous areolar tissue and a draining vein; Group 2 (n = 10), perivenous areolar tissue, a draining vein and nerve; Group 3 (n = 10), only perivenous areolar tissue. Macroscopic, angiographic and histological assessments were performed 14 days after transfer. The total survival areas including superficial necrosis of Groups 1, 2 and 3 were 52.7%, 82.5% and 0%, respectively. There were significant differences in mean survival area and mean total survival area including superficial necrosis between Group 1 and Group 2 (P < 0.05). In contrast, all flaps in Group 3 became necrotic. These data suggest that a preserved vein is the necessary condition, and additional arterial flow through the preserved nerve and a small vascular network within the areolar tissue may play an important role in flap survival.
在本文中，我们通过实验评估了带蒂静脉瓣与静脉周围乳晕组织转移至异位部位的可行性，并研究了每条静脉、静脉周围乳晕组织和神经在带蒂静脉瓣存活中的作用。使用兔耳模型创建了三组皮瓣：第1组（n = 11），包含静脉周围乳晕组织和引流静脉；第2组（n = 10），静脉周围乳晕组织、引流静脉和神经；第3组（n = 10），仅含静脉周围乳晕组织。转移14天后进行宏观、血管造影和组织学评估。第1、2和3组包括浅表坏死的总存活面积分别为52.7%、82.5%和0%。第1组和第2组之间的平均存活面积以及包括浅表坏死的平均总存活面积存在显著差异（P < 0.05）。相比之下，第3组的所有皮瓣均发生坏死。这些数据表明，保留的静脉是必要条件，通过保留的神经和乳晕组织内的小血管网络的额外动脉血流可能在皮瓣存活中起重要作用。
