Noreldin A A, Fukuta K, Jackson I T
Institute for Craniofacial and Reconstructive Surgery, Providence Hospital, Southfield.
Br J Plast Surg. 1992 Jan;45(1):18-22. doi: 10.1016/0007-1226(92)90108-a.
This study was performed to investigate how the perivenous areolar tissue affects survival of the rat inferior epigastric venous flap model designed by Yuen and Leung (1991). Five groups of flaps were studied; group A--flap based on an inferior epigastric vein and areolar tissue; group B--flap with a skeletonised vein; group C--control, nonvascularised flap; group D--flap based on perivascular areolar tissue alone; group E--flap with a skeletonised artery and vein. Each group included 40 flaps; 20 of them had a silicone sheet placed under the flap, the other 20 did not. All flaps of group E survived. The success rate of group A with and without a silicone sheet was 60% and 90% respectively. All flaps of the other groups (B, C, D) necrosed. Histological examination of the pedicle showed that many minute vascular channels (single-cell-layered capillaries) were present apart from the inferior epigastric vein. This result confirms the importance of the perivenous areolar tissue in perfusion of the skin island, at least, in the inferior epigastric venous flap in the rat.
本研究旨在探讨静脉周围乳晕组织如何影响由Yuen和Leung（1991年）设计的大鼠腹壁下静脉皮瓣模型的存活情况。研究了五组皮瓣；A组——以腹壁下静脉和乳晕组织为蒂的皮瓣；B组——静脉骨骼化的皮瓣；C组——对照，非血管化皮瓣；D组——仅以血管周围乳晕组织为蒂的皮瓣；E组——动静脉骨骼化的皮瓣。每组包括40个皮瓣；其中20个在皮瓣下放置了硅胶片，另外20个没有。E组所有皮瓣均存活。A组有硅胶片和无硅胶片时的成功率分别为60%和90%。其他组（B、C、D）的所有皮瓣均坏死。对蒂部的组织学检查显示，除腹壁下静脉外，还存在许多微小的血管通道（单细胞层毛细血管）。这一结果证实了静脉周围乳晕组织在皮岛灌注中的重要性，至少在大鼠腹壁下静脉皮瓣中是如此。
