从咽喉拭子中分离出的C组链球菌：一项实验室与临床研究。
Group C streptococci isolated from throat swabs: a laboratory and clinical study.
作者信息
Lewis R F, Balfour A E
机构信息
Microbiology Department, Victoria Infirmary, Glasgow, UK.
出版信息
J Clin Pathol. 1999 Apr;52(4):264-6. doi: 10.1136/jcp.52.4.264.
AIMS
To determine the prevalence of beta haemolytic, Lancefield group C streptococci in throat swabs taken in routine clinical practice, and correlate the species identified with presenting clinical features.
METHODS
One year, laboratory based prospective study, using a questionnaire to elicit clinical information.
RESULTS
4.4% of throat swabs yielded group C streptococci, of which 38% belonged to S equisimilis and 53% to S anginosus-milleri group (SAM). Pyrexia was more common in patients with S equisimilis, but other clinical features did not differ significantly between the two groups. No S zooepidemicus was isolated.
CONCLUSIONS
Species identification of group C streptococci from throat swabs does not appear to be clinically useful in this patient population. However, the prevalence and spectrum of organisms is similar to that reported in N America, where studies suggest a possible role in some cases of severe pharyngitis. Observational studies such as this lack power to resolve the issue of pathogenicity, for which a placebo controlled trial of antibiotic treatment is ideally required.
目的
确定在常规临床实践中采集的咽拭子中β溶血性C群链球菌的患病率，并将鉴定出的菌种与呈现的临床特征相关联。
方法
基于实验室的为期一年的前瞻性研究，使用问卷获取临床信息。
结果
4.4%的咽拭子培养出C群链球菌，其中38%属于似马链球菌，53%属于咽峡炎链球菌-米勒链球菌群（SAM）。似马链球菌感染患者发热更为常见，但两组间其他临床特征无显著差异。未分离出兽疫链球菌。
结论
在该患者群体中，从咽拭子中鉴定C群链球菌的菌种在临床上似乎并无用处。然而，微生物的患病率和种类与北美报道的相似，在北美，研究表明其在某些严重咽炎病例中可能起作用。此类观察性研究缺乏解决致病性问题的能力，对此理想情况下需要进行抗生素治疗的安慰剂对照试验。
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