Turner J C, Fox A, Fox K, Addy C, Garrison C Z, Herron B, Brunson C, Betcher G
Thomson Student Health Center, School of Medicine, University of South Carolina, Columbia 29208.
J Clin Microbiol. 1993 Apr;31(4):808-11. doi: 10.1128/jcm.31.4.808-811.1993.
All Lancefield group C beta-hemolytic streptococci isolated over 12 months from college students with clinical pharyngitis and age-matched healthy controls were identified. Clinical features of upper respiratory tract infection and pyogenic pharyngitis as well as colony counts were tabulated for each patient according to throat culture results. Of 1,480 patients, Lancefield group C Streptococcus equisimilis was isolated from 45 (3%) patients and Streptococcus anginosus ("Streptococcus milleri") was isolated from 164 (11.1%) patients. Patients from whom S. equisimilis was isolated had clinical features more suggestive of pyogenic infection than did patients from whom S. anginosus was isolated. Colony counts on primary throat culture plates from patients from whom S. equisimilis and Streptococcus pyogenes were isolated were higher than those from patients from whom S. anginosus was isolated. This study presents epidemiologic evidence supporting a role for S. equisimilis in causing pharyngeal infection and for S. anginosus as representing part of the normal oropharyngeal flora.
对在12个月期间从患有临床咽炎的大学生以及年龄匹配的健康对照者中分离出的所有兰斯菲尔德C组β溶血性链球菌进行了鉴定。根据咽拭子培养结果，将每位患者的上呼吸道感染和化脓性咽炎的临床特征以及菌落计数制成表格。在1480名患者中，从45名（3%）患者中分离出了类马链球菌（兰斯菲尔德C组链球菌），从164名（11.1%）患者中分离出了咽峡炎链球菌（“米勒链球菌”）。与分离出咽峡炎链球菌的患者相比，分离出类马链球菌的患者的临床特征更提示化脓性感染。从分离出类马链球菌和化脓性链球菌的患者的初次咽拭子培养平板上的菌落计数高于从分离出咽峡炎链球菌的患者。本研究提供了流行病学证据，支持类马链球菌在引起咽部感染中的作用，以及咽峡炎链球菌作为正常口咽部菌群一部分的代表。
