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先天性二尖瓣关闭不全的交界折叠环缩成形术的长期效果

The long-term results of commissure plication annuloplasty for congenital mitral insufficiency.

作者信息

Ohno H, Imai Y, Terada M, Hiramatsu T

机构信息

Department of Pediatric Cardiovascular Surgery, The Heart Institute of Japan, Tokyo Women's Medical University.

出版信息

Ann Thorac Surg. 1999 Aug;68(2):537-41. doi: 10.1016/s0003-4975(99)00515-9.

Abstract

BACKGROUND

Mitral valve repair in the pediatric population remains demanding because of a diversity of apparatus anomalies and the young age of the patients.

METHODS

We reviewed our clinical results for mitral valve repairs for congenital mitral insufficiency. Forty-nine consecutive patients aged 2 months to 34 years (mean, 4.4 years) had mitral valve repair between June 1984 and December 1996. Forty-one patients (83.7%) had associated cardiac anomalies. The predominant pathologies for the regurgitations were chordal anomalies in 34 patients (69%), annular dilatation in 8 (16%), and leaflet anomalies in 7 (14%). Mitral valve repair included commissure plication annuloplasty in 43 patients (88%), modified DeVega in 11, cleft closure in 5, plication of the anterior leaflet in 3, triangular resection of the anterior leaflet in 2, chordal shortening in 1, and placement of artificial chordae in 1. Several combined techniques were required in 19 patients.

RESULTS

There were no early or late deaths. The follow-up period was from 6 to 166 months (mean, 88.4 months). Forty-seven patients (95.9%) were in New York Heart Association class I. The long-term echocardiographic studies showed that 2 of 30 patients without reoperation had moderate regurgitation. The actuarial freedom from reoperation was 85.6% (95% confidence limits, 72.8%, 98.4%) at 13 years. Five patients (10.2%) required valve replacement from 13 days to 75 months after the valve repair. Two patients had cerebral ischemic events as a result of cardiomegaly and atrial fibrillation.

CONCLUSIONS

Valve repair for congenital mitral insufficiency gave adequate results in combination with commissure plication annuloplasty and other techniques with excellent long-term functional status.

摘要

背景

由于二尖瓣装置存在多种异常且患者年龄较小,小儿二尖瓣修复手术仍然具有挑战性。

方法

我们回顾了先天性二尖瓣关闭不全二尖瓣修复的临床结果。1984年6月至1996年12月期间,连续49例年龄在2个月至34岁(平均4.4岁)的患者接受了二尖瓣修复手术。41例患者(83.7%)伴有心脏其他异常。反流的主要病理类型为:34例(69%)腱索异常,8例(16%)瓣环扩张,7例(14%)瓣叶异常。二尖瓣修复包括43例(88%)患者行交界折叠环缩术,11例行改良德维加术,5例行裂口闭合术,3例行前叶折叠术,2例行前叶三角形切除术,1例行腱索缩短术,1例行人工腱索植入术。19例患者需要采用多种联合技术。

结果

无早期或晚期死亡病例。随访时间为6至166个月(平均88.4个月)。47例患者(95.9%)心功能为纽约心脏协会I级。长期超声心动图研究显示,30例未再次手术的患者中有2例存在中度反流。13年时再次手术的实际免手术率为85.6%(95%可信区间,72.8%,98.4%)。5例患者(10.2%)在瓣膜修复术后13天至75个月需要进行瓣膜置换。2例患者因心脏扩大和心房颤动发生脑缺血事件。

结论

先天性二尖瓣关闭不全的瓣膜修复结合交界折叠环缩术和其他技术可取得满意效果,长期功能状态良好。

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