Noon G P, Lafuente J A, Irwin S
Department of Surgery, Baylor College of Medicine, The Methodist Hospital, Houston, Texas, USA.
Ann Thorac Surg. 1999 Aug;68(2):650-4. doi: 10.1016/s0003-4975(99)00580-9.
Short-term ventricular and pulmonary support can be provided by the Medtronic BioMedicus (Eden Prairie, MN) centrifugal pump, which is available in most cardiovascular surgery centers. This versatile pump can provide support during cardiopulmonary resuscitation, cardiopulmonary bypass, extracorporeal membrane oxygenation, and ventricular assistance. A common use of the pump is to provide ventricular assistance for patients after cardiotomy or cardiogenic shock.
From January 1986 to September 1995, 141 patients at The Methodist Hospital in Houston, Texas were placed on the BioMedicus centrifugal pump after postcardiotomy cardiac failure. Patient treatment and postimplant complications are discussed.
Fifty-four percent of the patients were weaned; however, only 22% survived to discharge. There was a very high mortality rate in the early stage after support was discontinued, after weaning, and after device removal.
A high incidence of complications and death is likely related to the period of attempted weaning from cardiopulmonary bypass before the initiation of ventricular support. When weaning a patient from the pump during cardiopulmonary bypass or during ventricular assistance, it is important to optimize preload, after-load, ventricular function, and cardiac rhythm. In patients who have had postcardiotomy support, avoiding fluid overload, low colloid oncotic pressure, hypoperfusion, and use of excessive inotropic and vasoactive medications improve results.
美敦力百多力(明尼苏达州伊甸草原市)离心泵可为患者提供短期心室和肺部支持,大多数心血管外科中心都配备了这种设备。这种多功能泵可在心肺复苏、体外循环、体外膜肺氧合及心室辅助期间提供支持。该泵的一种常见用途是为心脏切开术后或心源性休克患者提供心室辅助。
1986年1月至1995年9月,得克萨斯州休斯敦卫理公会医院的141例患者在心脏切开术后出现心力衰竭,接受了百多力离心泵治疗。本文讨论了患者的治疗情况及植入后的并发症。
54%的患者成功撤机;然而,只有22%的患者存活出院。在停止支持、撤机及移除设备后的早期,死亡率非常高。
并发症和死亡的高发生率可能与在开始心室支持前尝试从体外循环撤机的阶段有关。在体外循环期间或心室辅助期间为患者撤机时,优化前负荷、后负荷、心室功能及心律非常重要。对于接受过心脏切开术后支持的患者,避免液体超负荷、低胶体渗透压、灌注不足以及使用过量的强心剂和血管活性药物可改善治疗效果。