Tanehata M, Adachi H, Oshima S, Taniguchi K, Itoh H, Hasegawa A, Nagai R
The Second Department of Internal Medicine, Gunma University School of Medicine, Japan.
Jpn Circ J. 1999 Apr;63(4):274-7. doi: 10.1253/jcj.63.274.
The significance of the time from anaerobic threshold to respiratory compensation point (RCP-AT time) in patients with chronic heart failure was investigated. Thirty-seven patients with chronic heart failure (New York Heart Association class II or III) were enrolled into the study. Cardiopulmonary exercise testing was performed using breath-by-breath gas sampling. A bicycle ergometer was used, and incremental exercise testing was carried out. Anaerobic threshold, respiratory compensation point (RCP), and the slope of oxygen uptake (VO2) as a function of work rate (deltaVO2/deltaWR) were measured. A positive correlation (r=0.53) between RCP-AT time and deltaVO2/deltaWR was found. RCP-AT time was corrected for the whole exercise period (ramp exercise-RCP point), and the correlation between corrected RCP-AT time and deltaVO2/deltaWR was still present (r=0.46). There was no correlation between RCP-AT time and anaerobic threshold. These findings suggest that RCP-AT time is a new parameter that reflects the rate of the aerobic and anaerobic metabolism after AT.
研究了慢性心力衰竭患者从无氧阈到呼吸补偿点的时间（RCP-AT时间）的意义。37例慢性心力衰竭患者（纽约心脏协会II或III级）纳入本研究。采用逐次呼吸气体采样进行心肺运动试验。使用自行车测力计进行递增运动试验。测量无氧阈、呼吸补偿点（RCP）以及摄氧量（VO2）作为工作率函数的斜率（deltaVO2/deltaWR）。发现RCP-AT时间与deltaVO2/deltaWR之间存在正相关（r=0.53）。将RCP-AT时间校正为整个运动期（斜坡运动-RCP点），校正后的RCP-AT时间与deltaVO2/deltaWR之间仍存在相关性（r=0.46）。RCP-AT时间与无氧阈之间无相关性。这些发现表明，RCP-AT时间是一个反映无氧阈后有氧和无氧代谢速率的新参数。
