Rampen F
Br J Vener Dis. 1978 Dec;54(6):364-8. doi: 10.1136/sti.54.6.364.
A steady decline in the incidence of positive results to the Kahn test is reported in Malawian patients during the period 1968-75. Other studies have shown that the incidence of early and late syphilis in sub-Saharan Africa has dropped considerably over the past few decades. The number of reported cases of early syphilis in certain urban areas, however, appears to be high. It is suggested that the downward trend in the incidence of syphilis in Africa is related to the increased and often indiscriminate use of penicillin.
据报道,1968年至1975年期间,马拉维患者康氏试验阳性结果的发生率呈稳步下降趋势。其他研究表明,在过去几十年中,撒哈拉以南非洲地区早期和晚期梅毒的发病率大幅下降。然而,某些城市地区报告的早期梅毒病例数似乎较高。有人认为,非洲梅毒发病率的下降趋势与青霉素使用的增加且往往是不加区分的使用有关。