De la Peña J, Sánchez Hernández E, Rivero M, Martínez Argüelles B, Mazarrasa C, Horna R, Pons Romero F
Servicio de Aparato Digestivo, Hospital Universitario "Marqués de Valdecilla", Santander, Cantabria, España.
Rev Esp Enferm Dig. 1999 Jul;91(7):489-96.
Gastrointestinal endoscopy can lead to infectious complications, and endoscopes must be disinfected to prevent them.
to evaluate three methods of disinfection: 1) usual cleaning technique and immersion in glutaraldehyde phenolate (GP); 2) meticulous cleaning and immersion in GP, and 3) meticulous cleaning and immersion in hydrogen peroxide.
thirty endoscopes (15 gastroscopes and 15 colonoscopes) were disinfected with each method. Samples were taken following endoscopic exploration, after cleaning and after disinfection, and were cultured. The number of positive culture (cfu/ml > 1) was counted.
the rate of contamination of endoscopes did not decrease significantly after cleaning with method 1 (66 vs 60%), but did decrease with method 2 (38 vs 16%) and method 3 (53 vs 17%). The contamination rate after cleaning was significantly lower with methods 2 and 3 (p < 0.005). This rate was also lower after disinfection (p < 0.025). Method 3 achieved 0% contamination following disinfection.
the greatest decrease in contamination rate was achieved with conscientious cleaning followed by disinfection. Both disinfectants yielded similar results, although hydrogen peroxide produced a higher level of disinfection.
胃肠内镜检查可能导致感染并发症，因此必须对内镜进行消毒以预防此类情况。
评估三种消毒方法：1）常规清洁技术并浸泡于戊二醛酚盐（GP）中；2）细致清洁并浸泡于GP中；3）细致清洁并浸泡于过氧化氢中。
每种方法对30条内镜（15条胃镜和15条结肠镜）进行消毒。在内镜检查后、清洁后及消毒后采集样本并进行培养。计算阳性培养物数量（cfu/ml > 1）。
方法1清洁后内镜污染率未显著降低（66%对60%），但方法2（38%对16%）和方法3（53%对17%）清洁后污染率降低。方法2和3清洁后的污染率显著更低（p < 0.005）。消毒后的污染率也更低（p < 0.025）。方法3消毒后污染率为0%。
认真清洁后再消毒能使污染率下降幅度最大。两种消毒剂效果相似，不过过氧化氢消毒水平更高。
