梗阻性无精子症患者精子提取及卵胞浆内单精子注射的结果：既往结核性附睾炎的影响
The outcome of sperm retrieval and intracytoplasmic sperm injection in patients with obstructive azoospermia: impact of previous tuberculous epididymitis.
作者信息
Moon S Y, Kim S H, Jee B C, Jung B J, Suh C S, Lee J Y
机构信息
Department of Obstetrics and Gynecology, College of Medicine, Seoul National University, Korea.
出版信息
J Assist Reprod Genet. 1999 Sep;16(8):431-5. doi: 10.1023/a:1020521625765.
PURPOSE
Our purpose was to investigate the influence of previous tuberculous epididymitis in patients with obstructive azoospermia on the outcome of sperm retrieval and intracytoplasmic sperm injection (ICSI).
METHODS
Eighty-eight cycles of ICSI were performed in 44 patients with obstructive azoospermia; 16 cycles (7 patients) with tuberculous obstructive azoospermia and 72 cycles (37 patients) with nontuberculous obstructive azoospermia.
RESULTS
The rates of fertilization and embryo cleavage were comparable, and there was no significant difference in the clinical pregnancy rate per fresh transfer between the two groups. The rates of embryo implantation and clinical miscarriage were also comparable.
CONCLUSIONS
Embryo quality and pregnancy outcome in sperm retrieval and ICSI were comparable in both the tuberculous and the nontuberculous obstructive azoospermia patients. Although there was a preponderance of testicular sperm used in the tuberculous obstructive azoospermia group, our results suggest that previous tuberculous epididymitis in patients with obstructive azoospermia does not affect the outcome of sperm retrieval and ICSI.
目的
我们的目的是研究既往结核性附睾炎对梗阻性无精子症患者取精及卵胞浆内单精子注射（ICSI）结局的影响。
方法
对44例梗阻性无精子症患者进行了88个周期的ICSI；其中16个周期（7例患者）为结核性梗阻性无精子症，72个周期（37例患者）为非结核性梗阻性无精子症。
结果
两组的受精率和胚胎分裂率相当，新鲜移植后的临床妊娠率无显著差异。胚胎着床率和临床流产率也相当。
结论
结核性和非结核性梗阻性无精子症患者在取精及ICSI中的胚胎质量和妊娠结局相当。尽管结核性梗阻性无精子症组使用睾丸精子的比例较高，但我们的结果表明，既往结核性附睾炎对梗阻性无精子症患者的取精及ICSI结局无影响。
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