Palmer B W, Heaton S C, Jeste D V
Department of Psychiatry at the University of California, San Diego, USA.
Psychiatr Serv. 1999 Sep;50(9):1178-83. doi: 10.1176/ps.50.9.1178.
The number and proportion of older adults with schizophrenia will increase considerably in the coming decades. Although a vast literature on schizophrenia among younger adults exists, much less is known about late-life schizophrenia and its treatment. The authors describe two potential scenarios for 2011, the year that the first baby boomers will turn 65. To ensure that the more favorable scenario becomes a reality, the authors suggest four goals: decrease medical comorbidity and mortality among younger patients with schizophrenia and improve their access to health care so that they can live longer and more productive lives; improve our understanding of the neurobiological and psychosocial factors underlying late-life schizophrenia, as well as the health care and social service needs of such patients; develop more effective and safer pharmacologic, psychosocial, and cognitive behavioral treatments; and improve rehabilitation of older people with schizophrenia. Specific strategies to foster these goals include establishing a consortium for studies of late-life schizophrenia; conducting multicenter studies of treatment effectiveness; and forming interdisciplinary collaborations among researchers, clinicians, government and industry representatives, and patient advocacy groups.
在未来几十年里，患有精神分裂症的老年人数量及其所占比例将大幅增加。尽管有大量关于年轻成年人精神分裂症的文献，但对于老年期精神分裂症及其治疗的了解却少得多。作者描述了2011年（第一批婴儿潮一代将年满65岁的那一年）可能出现的两种情况。为确保更有利的情况成为现实，作者提出了四个目标：降低年轻精神分裂症患者的医疗合并症和死亡率，改善他们获得医疗保健的机会，以便他们能够活得更长、更有成效；增进我们对老年期精神分裂症潜在的神经生物学和心理社会因素的理解，以及此类患者的医疗保健和社会服务需求；开发更有效、更安全的药物、心理社会和认知行为治疗方法；改善老年精神分裂症患者的康复情况。促进这些目标实现的具体策略包括成立一个老年期精神分裂症研究联盟；开展治疗效果的多中心研究；以及在研究人员、临床医生、政府和行业代表以及患者倡导团体之间建立跨学科合作。
