Dargis V, Pantelejeva O, Jonushaite A, Vileikyte L, Boulton A J
Rehabilitation Hospital, Kaunas, Lithuania.
Diabetes Care. 1999 Sep;22(9):1428-31. doi: 10.2337/diacare.22.9.1428.
To assess the ability of a multidisciplinary approach to diabetic foot care to reduce the incidence of recurrent ulceration and amputations compared with standard care in a 2-year prospective study.
A total of 145 patients with a past history of neuropathic foot ulcers but no evidence of peripheral vascular disease entered the study. Subjects were screened for their neuropathic and vascular status at baseline, and all received identical foot care education. The intervention group (n = 56) was followed by the multidisciplinary team of physicians, nurses, and podiatrists with regular podiatry and reeducation every 3 months and the provision of specialty footwear as required. The standard treatment group was followed in local clinics on a trimonthly basis and received identical screening and education at baseline.
There were no significant differences at baseline in age (intervention 59.2+/-13.4, standard treatment 58.5+/-11.5 years), duration of diabetes (14.0+/-7.1 vs. 15.6+/-7.8 years), or neuropathic status (vibration perception threshold [VPT]: 31.1+/-12.1 vs. 33.9+/-11.3 V, neuropathy disability score [NDS]: 8.1+/-1.4 vs. 7.9+/-1.7). All patients had an ankle brachial pressure index (ABPI) of >0.9 and at least one palpable foot pulse. Significantly fewer recurrent ulcers were seen in the intervention group than in the standard treatment group during the 2-year period (30.4 vs. 58.4%, P < 0.001).
This prospective study has demonstrated the effectiveness of a multidisciplinary approach to diabetic foot care together with the provision of specialty footwear in the long-term management of high-risk patients with a history of neuropathic foot ulcers.
在一项为期2年的前瞻性研究中,评估与标准护理相比,多学科方法进行糖尿病足护理降低复发性溃疡和截肢发生率的能力。
共有145例有神经性足部溃疡病史但无外周血管疾病证据的患者进入研究。在基线时对受试者的神经病变和血管状况进行筛查,所有患者均接受相同的足部护理教育。干预组(n = 56)由医生、护士和足病医生组成的多学科团队进行随访,每3个月进行一次常规足病治疗和再教育,并根据需要提供特制鞋具。标准治疗组每三个月在当地诊所接受随访,并在基线时接受相同的筛查和教育。
两组在基线时的年龄(干预组59.2±13.4岁,标准治疗组58.5±11.5岁)、糖尿病病程(14.0±7.1年 vs. 15.6±7.8年)或神经病变状况(振动觉阈值[VPT]:31.1±12.1 V vs. 33.9±11.3 V,神经病变残疾评分[NDS]:8.1±1.4 vs. 7.9±1.7)方面无显著差异。所有患者的踝肱压力指数(ABPI)均>0.9,且至少有一个可触及的足部脉搏。在2年期间,干预组的复发性溃疡明显少于标准治疗组(30.4%对58.4%,P<0.001)。
这项前瞻性研究证明了多学科方法进行糖尿病足护理以及提供特制鞋具在有神经性足部溃疡病史的高危患者长期管理中的有效性。