Bullimore M A, Olson M D, Maloney R K
College of Optometry, Ohio State University, Columbus, USA.
Am J Ophthalmol. 1999 Jul;128(1):1-7. doi: 10.1016/s0002-9394(99)00077-x.
To prospectively examine the effect of photorefractive keratectomy with a 6-mm ablation zone on best-spectacle-corrected visual performance.
A prospective study was conducted of 164 eyes of 164 patients with an average (+/-SD) of -4.02 +/- 1.74 diopters (range, -0.63 to -8.38 diopters spherical equivalent). Best-spectacle-corrected high-contrast and low-contrast visual acuity (18% Weber contrast) was measured with both natural and dilated pupils. Patients were tested preoperatively and at 3, 6, and 12 months after photorefractive keratectomy. Photorefractive keratectomy was performed with an argon fluoride excimer laser. Fifty-five eyes of 55 patients also underwent astigmatic keratotomy.
Twelve months after photorefractive keratectomy, best-spectacle-corrected high-contrast visual acuity with natural pupils showed no significant change from preoperative values; mean (+/-SD) change was 0.004 +/- 0.10 logMAR (t = 0.45, P = .65). Best-spectacle-corrected low-contrast visual acuity with natural pupils was significantly reduced compared to baseline; mean (+/-SD) change was 0.04 +/- 0.13 logMAR (t = 3.3, P = .001). The low-contrast loss was larger (1.5 lines) with dilated pupils; mean (+/-SD) change was 0.13 +/- 0.15 logMAR (t = 9.31, P < .001). Greater losses in dilated low-contrast visual acuity were associated with concurrent astigmatic ketatotomy (t = 2.28, P = .025) and corneal haze of grade 1 or greater (t = 2.71, P = .005).
Reductions in visual performance occur after photorefractive keratectomy with a 6-mm zone. These changes are greatest for low-contrast visual acuity with dilated pupils. Corneal haze and concurrent astigmatic keratotomy are associated with greater losses in low-contrast visual acuity. Best-spectacle-corrected low-contrast visual acuity is a sensitive measure for evaluating visual performance after refractive surgery.
前瞻性研究6毫米消融区的准分子激光原位角膜磨镶术(PRK)对最佳矫正视力的影响。
对164例患者的164只眼进行前瞻性研究,平均(±标准差)等效球镜度数为-4.02±1.74屈光度(范围为-0.63至-8.38屈光度)。在自然瞳孔和散瞳状态下测量最佳矫正高对比度和低对比度视力(18%韦伯对比度)。患者在术前以及PRK术后3、6和12个月进行测试。使用氟化氩准分子激光进行PRK。55例患者的55只眼还接受了散光性角膜切开术。
PRK术后12个月,自然瞳孔状态下最佳矫正高对比度视力与术前值相比无显著变化;平均(±标准差)变化为0.004±0.10最小分辨角对数(t = 0.45,P = 0.65)。自然瞳孔状态下最佳矫正低对比度视力与基线相比显著降低;平均(±标准差)变化为0.04±0.13最小分辨角对数(t = 3.3,P = 0.001)。散瞳状态下低对比度视力损失更大(1.5行);平均(±标准差)变化为0.13±0.15最小分辨角对数(t = 9.31,P < 0.001)。散瞳状态下低对比度视力损失更大与同时进行散光性角膜切开术(t = 2.28,P = 0.025)以及1级或更高级别的角膜混浊相关(t = 2.71,P = 0.005)。
6毫米区域的PRK术后视力会下降。这些变化在散瞳状态下的低对比度视力中最为明显。角膜混浊和同时进行的散光性角膜切开术与低对比度视力的更大损失相关。最佳矫正低对比度视力是评估屈光手术后视力的敏感指标。