Verdon W, Bullimore M, Maloney R K
Jules Stein Eye Institute, University of California, Los Angeles, USA.
Arch Ophthalmol. 1996 Dec;114(12):1465-72. doi: 10.1001/archopht.1996.01100140663003.
To prospectively examine the effect of excimer laser photorefractive keratectomy (PRK) on best-corrected visual performance using psychophysical tests that were likely to be more sensitive to image degradation than high-contrast Snellen visual acuity.
Prospective cases series.
A cohort of 18 subjects with an average of -5.08 diopters (D) of myopia (SD = +/- 1.63 D) was tested before PRK and at 3, 6, and 12 months after PRK.
Photorefractive keratectomy was performed using a laser (Excimed UV200, Summit Technology, Waltham, Mass) and a polymethylmethacrylate mask; a 5-mm ablation zone was used.
Best-corrected high-contrast visual acuity, best-corrected low-contrast visual acuity (18% Weber contrast), and best-corrected letter-contrast sensitivity. Measurements were repeated with dilated pupils and in the presence of a glare source.
One year after PRK, the mean best-corrected high-contrast visual acuity was reduced by half a line (P = .01), and the mean best-corrected low-contrast visual acuity was reduced by 1 1/2 lines (P = .002). The losses were somewhat greater when the subject's pupils were dilated and a glare source was used. The reduction in dilated low-contrast visual acuity was positively correlated with the decentration of the ablation zone (r = 0.47), providing evidence of an association between corneal topography and the functional outcome of PRK.
Low-contrast visual acuity losses after PRK are notably greater than high-contrast visual acuity losses for best-corrected vision. Low-contrast visual acuity is a sensitive measure for gauging the outcome success and safety of refractive surgery.
采用可能比高对比度斯内伦视力对图像退化更敏感的心理物理学测试,前瞻性地研究准分子激光屈光性角膜切削术(PRK)对最佳矫正视力的影响。
前瞻性病例系列研究。
选取18例平均近视度数为-5.08屈光度(D)(标准差=±1.63 D)的受试者,在PRK术前以及术后3个月、6个月和12个月进行测试。
使用激光(Excimed UV200,Summit Technology,马萨诸塞州沃尔瑟姆)和聚甲基丙烯酸甲酯面罩进行屈光性角膜切削术;采用5毫米的消融区。
最佳矫正高对比度视力、最佳矫正低对比度视力(18%韦伯对比度)和最佳矫正字母对比度敏感度。在散瞳状态下以及存在眩光光源的情况下重复测量。
PRK术后1年,平均最佳矫正高对比度视力下降了半行(P = 0.01),平均最佳矫正低对比度视力下降了1.5行(P = 0.002)。当受试者瞳孔散大并使用眩光光源时,视力下降幅度更大。散瞳后低对比度视力的下降与消融区的偏心程度呈正相关(r = 0.47),这为角膜地形图与PRK的功能结果之间的关联提供了证据。
PRK术后低对比度视力损失明显大于最佳矫正视力的高对比度视力损失。低对比度视力是衡量屈光手术结果成功与否和安全性的一项敏感指标。