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由分泌促肾上腺皮质激素的胸腺恶性类癌瘤引起的皮质类固醇性青光眼。

Corticosteroid-induced glaucoma attributable to an adrenocorticotropin-secreting malignant carcinoid tumor of the thymus.

作者信息

Blumenthal E Z, Muszkat M, Pe'er J, Ticho U

机构信息

Department of Ophthalmology, Hadassah University Hospital and Hebrew University-Hadassah Medical School, Jerusalem, Israel.

出版信息

Am J Ophthalmol. 1999 Jul;128(1):100-1. doi: 10.1016/s0002-9394(99)00052-5.

Abstract

PURPOSE

To describe the clinical and histopathologic findings in a patient with corticosteroid-induced open-angle glaucoma attributable to an adrenocorticotropin-secreting malignant carcinoid of the thymus.

METHODS

Case report. In a 33-year-old man, the clinical course, laboratory findings, and imaging results as well as the histopathologic findings are described.

RESULTS

Increased intraocular pressure in this patient represented a manifestation of severe hypercortisolism attributable to a malignant adrenocorticotropin-secreting carcinoid tumor. Surgical removal resulted in return of the intraocular pressure values to normal levels.

CONCLUSION

Thymic carcinoid is a rare cause of Cushing syndrome, which can lead to increased intraocular pressure.

摘要

目的

描述一例因分泌促肾上腺皮质激素的胸腺恶性类癌导致皮质类固醇性开角型青光眼患者的临床和组织病理学表现。

方法

病例报告。描述一名33岁男性患者的临床病程、实验室检查结果、影像学结果以及组织病理学表现。

结果

该患者眼压升高是由分泌促肾上腺皮质激素的恶性类癌肿瘤导致的严重皮质醇增多症的一种表现。手术切除后眼压值恢复正常水平。

结论

胸腺类癌是库欣综合征的罕见病因,可导致眼压升高。

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