通过牙髓电测试确定哌替啶、萘普生钠和对乙酰氨基酚对疼痛阈值的影响。
Change in pain threshold by meperidine, naproxen sodium, and acetaminophen as determined by electric pulp testing.
作者信息
Carnes P L, Cook B, Eleazer P D, Scheetz J P
机构信息
University of Louisville School of Dentistry, KY 40292, USA.
出版信息
Anesth Prog. 1998 Fall;45(4):139-42.
Abstract
The purpose of this study was to compare changes in pain threshold caused by meperidine, naproxen sodium, acetaminophen, and placebo. The change in pain threshold was measured by electric pulp testing. Acetaminophen elevated the pain threshold statistically significantly. Clinically, however, the superiority of acetaminophen is questionable. No elevation of the pain threshold occurred with narcotic drugs or with nonsteroidal anti-inflammatory drugs: our research shows that the electric pulp tests of patients who have taken these drugs preoperatively will have results similar to those of patients who have taken no drugs. We question the philosophy of administering these drugs for change in pain threshold at the levels used here preoperatively.
摘要
本研究的目的是比较哌替啶、萘普生钠、对乙酰氨基酚和安慰剂引起的痛阈变化。通过牙髓电测试来测量痛阈变化。对乙酰氨基酚使痛阈有统计学意义的升高。然而，在临床上，对乙酰氨基酚的优势值得怀疑。麻醉药物和非甾体抗炎药均未使痛阈升高：我们的研究表明，术前服用这些药物的患者的牙髓电测试结果与未服药患者的结果相似。我们质疑术前在此水平使用这些药物以改变痛阈的理念。
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