Reinvang I
Department of Psychology, University of Oslo, Norway.
J Clin Exp Neuropsychol. 1998 Dec;20(6):885-97. doi: 10.1076/jcen.20.6.885.1106.
The relationship between behavioral reaction time (RT) and event related potential (ERP) variables (N2, P3) measuring perceptual and attentional processing was studied in continuous performance tasks (CPT). ERPs provide on-line measures of cerebral processing and the purpose of the study was to provide normative data and to use ERP-derived information to facilitate interpretation of reaction time data. In Study 1 a normal group (N = 51) performed CPTs of varying complexity, and the results indicated that in simple tasks a fast process reflecting perceptual classification and orientation of attention (N2) is involved, whereas a physiological marker of a controlled attention process reflected in P3 latency is related to RT in more complex tasks. In Study 2 normal subjects (N = 12) performed CPTs with instruction to deliberately vary RTs. Despite wide variation in behavioral RTs, ERP measures reflecting attention (N2,P3) show little influence of instruction, while late occuring components (SW) measured at fronto-central electrodes are affected. In neuropsychological assessment efforts have been made to develop symptom validity indicators, and the results show that ERPs are important measures for interpreting cerebral and motivational mechanisms underlying behavioral RTs.
在连续作业任务（CPT）中，研究了行为反应时间（RT）与测量感知和注意力加工的事件相关电位（ERP）变量（N2、P3）之间的关系。ERP提供大脑加工的在线测量，本研究的目的是提供规范数据，并使用源自ERP的信息来促进对反应时间数据的解释。在研究1中，一个正常组（N = 51）执行了不同复杂程度的CPT，结果表明，在简单任务中，涉及一个反映感知分类和注意力定向的快速过程（N2），而在更复杂任务中，P3潜伏期所反映的受控注意力过程的生理指标与RT相关。在研究2中，正常受试者（N = 12）执行CPT并被指示故意改变RT。尽管行为RT有很大差异，但反映注意力的ERP测量（N2、P3）受指示的影响很小，而在额中央电极测量的晚期成分（SW）则受到影响。在神经心理学评估中，已努力开发症状效度指标，结果表明，ERP是解释行为RT背后的大脑和动机机制的重要测量方法。
