Federici T J, Meyer D R, Lininger L L
Lions Eye Institute, Department of Ophthalmology, Albany Medical College, New York 12208, USA.
Ophthalmology. 1999 Sep;106(9):1705-12. doi: 10.1016/S0161-6420(99)90354-8.
To assess the effect of blepharoptosis on patients' visual function and health-related quality of life and to determine what measures are associated with postsurgical change in functional status.
Prospective, observational case series.
One hundred patients with unilateral or bilateral blepharoptosis. INTERVENTION/MAIN OUTCOME MEASURES: Preoperative and postoperative upper eyelid position (i.e., margin reflex distance [MRD]) and superior visual field (SVF) height, as well as subjective visual function and health-related quality-of-life functional status before and after ptosis surgery.
There was a mean 30-point increase in functional index score after ptosis repair (P < 0.001). Lower (more ptotic) preoperative upper eyelid position and SVF (combined eye) were associated with greater change in functional index after surgery (r = -0.290, P = 0.007 and r = -0.39, P = 0.003, respectively). Preoperative visual field testing with manual lid elevation was not significantly correlated to the postoperative change in functional index (P > 0.100). The strongest correlation of postoperative functional index change was with the preoperative functional status (r = -0.79, P < 0.001).
Patients' functional status is reduced by blepharoptosis, and surgical repair results in measurable increase in health-related quality of life. Patients' self-reported preoperative functional impairment is most strongly associated with the degree of postsurgical functional improvement.
评估上睑下垂对患者视觉功能及健康相关生活质量的影响,并确定哪些措施与术后功能状态的变化相关。
前瞻性观察性病例系列研究。
100名单侧或双侧上睑下垂患者。
干预措施/主要观察指标:术前及术后上睑位置(即缘反射距离[MRD])和上方视野(SVF)高度,以及上睑下垂手术前后的主观视觉功能和健康相关生活质量功能状态。
上睑下垂修复术后功能指数评分平均提高30分(P<0.001)。术前上睑位置较低(下垂更明显)和SVF(双眼合并)与术后功能指数的更大变化相关(分别为r = -0.290,P = 0.007和r = -0.39,P = 0.003)。术前手动提起眼睑进行视野测试与术后功能指数变化无显著相关性(P>0.100)。术后功能指数变化的最强相关性与术前功能状态相关(r = -0.79,P<0.001)。
上睑下垂会降低患者的功能状态,手术修复可使健康相关生活质量得到可测量的提高。患者术前自我报告的功能损害与术后功能改善程度的相关性最强。