Gokce H I, Woldehiwet Z
University of Liverpool, Department of Veterinary Pathology, Leahurst, Neston, S. Wirral, L64 7TE, UK.
J Comp Pathol. 1999 Oct;121(3):227-40. doi: 10.1053/jcpa.1999.0320.
Eight lambs experimentally infected with Ehrlichia (Cytoecetes) phagocytophila 7 days before exposure to orf virus were compared with control lambs infected with orf virus alone. The dually infected animals differed from the controls in showing skin lesions of greater severity, prolonged viral shedding, and lower antibody titres. Infection with E. phagocytophila had no significant effect on virus-specific lymphocyte proliferation. Such proliferation was detected in the peripheral blood of all lambs as early as 7 days after exposure to orf virus.
将8只在接触羊口疮病毒前7天经实验感染嗜吞噬细胞埃立克体（细胞埃立克体属）的羔羊与仅感染羊口疮病毒的对照羔羊进行比较。双重感染的动物与对照动物不同，表现为皮肤损伤更严重、病毒脱落时间延长且抗体滴度较低。嗜吞噬细胞埃立克体感染对病毒特异性淋巴细胞增殖没有显著影响。早在接触羊口疮病毒7天后，在所有羔羊的外周血中就检测到了这种增殖。
