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以呼吸肌无力为表现的近端糖尿病性神经病变

Proximal diabetic neuropathy presenting with respiratory weakness.

作者信息

Brannagan T H, Promisloff R A, McCluskey L F, Mitz K A

机构信息

MCP-Hahnemann University School of Medicine, Department of Neurology, Pennsylvania, Philadelphia 19102, USA.

出版信息

J Neurol Neurosurg Psychiatry. 1999 Oct;67(4):539-41. doi: 10.1136/jnnp.67.4.539.

DOI:10.1136/jnnp.67.4.539
PMID:10486409
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1736576/
Abstract

A patient is described with proximal diabetic neuropathy presenting with respiratory weakness. A 50 year old man developed progressive shortness of breath over 2 months. He also had weakness of hip flexion. Phrenic nerve responses were absent, and spontaneous activity was seen in the intercostal and lumbar paraspinal muscles with long duration neurogenic MUPs and reduced recruitment in the diaphragm. Without treatment, the patient began to improve with resolution of his proximal leg weakness and breathing difficulties. Proximal diabetic neuropathy is another cause of neuromuscular respiratory weakness.

摘要

描述了一名患有近端糖尿病性神经病变并伴有呼吸肌无力的患者。一名50岁男性在2个月内逐渐出现气短症状。他还存在屈髋肌无力。膈神经反应消失,在肋间肌和腰段椎旁肌可见自发活动,运动单位电位(MUP)时限长且为神经源性,膈肌募集减少。未经治疗,患者近端腿部无力和呼吸困难症状缓解,病情开始好转。近端糖尿病性神经病变是神经肌肉性呼吸肌无力的另一个原因。

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