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膀胱收缩通过喉上神经和肋间神经刺激改变吸气终止。

Bladder contractions alter inspiratory termination by superior laryngeal and intercostal nerve stimulation.

作者信息

Bartlett D, Knuth S L

机构信息

Department of Physiology, Dartmouth Medical School, Lebanon, NH 03756, USA.

出版信息

Respir Physiol. 1999 Aug 3;116(2-3):105-14. doi: 10.1016/s0034-5687(99)00040-7.

DOI:10.1016/s0034-5687(99)00040-7
PMID:10487296
Abstract

Gradual distension of the urinary bladder evokes spontaneous bladder contractions (SBCs), which are associated with reduced inspiratory activity in the phrenic and other inspiratory motor nerves. We examined the influence of isovolumetric SBCs on the threshold for termination of phrenic inspiration by electrical stimulation of superior laryngeal and/or mid-thoracic intercostal nerves (ICN) in decerebrate, vagotomized, paralyzed, ventilated cats. Although SBCs reduced phrenic inspiratory activity, the threshold for inspiratory termination by nerve stimulation was increased. The results emphasize the complexity of the synaptic connections among brain stem neurons governing micturition and breathing.

摘要

膀胱的逐渐扩张会引发自发性膀胱收缩(SBCs),这与膈神经和其他吸气运动神经的吸气活动减少有关。我们研究了等容性SBCs对通过电刺激去大脑、切断迷走神经、麻痹、通气猫的喉上神经和/或胸中段肋间神经(ICN)来终止膈神经吸气阈值的影响。尽管SBCs降低了膈神经的吸气活动,但神经刺激引起的吸气终止阈值却升高了。这些结果强调了控制排尿和呼吸的脑干神经元之间突触连接的复杂性。

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