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翼状胬肉切除术后铜绿假单胞菌性角膜巩膜炎的治疗

The treatment of Pseudomonas keratoscleritis after pterygium excision.

作者信息

Huang S C, Lai H C, Lai I C

机构信息

Department of Ophthalmology, Chang-Gung Memorial Hospital, Chang-Gung University, Taipei, Taiwan.

出版信息

Cornea. 1999 Sep;18(5):608-11.

Abstract

PURPOSE

To assess the effect of intensive topical and intravenous antibiotics plus oral prednisolone and surgical debridement in Pseudomonas keratoscleritis after pterygium excision.

METHODS

We describe three cases of P. aeruginosa-induced keratoscleritis occurring 10 days to 18 months after uncomplicated pterygium excision. Treatment included early conjunctival debridement, topical and intravenous antibiotics, and low-dosage oral prednisolone.

RESULTS

All three patients responded to the combined therapy. Microorganisms were eliminated, and ulcers were healed within 8 weeks. Treatment was not extended beyond that, and infection did not recur. No evisceration was required. The patients' best corrected visual acuities are 20/200, 20/400, and 20/120, respectively.

CONCLUSION

Early diagnosis and prompt, intensive medical and surgical treatment may save a patient's vision and forestall evisceration.

摘要

目的

评估强化局部及静脉使用抗生素联合口服泼尼松龙及手术清创治疗翼状胬肉切除术后铜绿假单胞菌性角膜巩膜炎的效果。

方法

我们描述了3例在单纯翼状胬肉切除术后10天至18个月发生的铜绿假单胞菌性角膜巩膜炎病例。治疗包括早期结膜清创、局部及静脉使用抗生素以及低剂量口服泼尼松龙。

结果

所有3例患者对联合治疗均有反应。微生物被清除,溃疡在8周内愈合。治疗未超过此期限,感染未复发。无需进行眼球摘除术。患者的最佳矫正视力分别为20/200、20/400和20/120。

结论

早期诊断并及时进行强化药物及手术治疗可挽救患者视力并避免眼球摘除术。

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