西班牙北部囚犯感染艾滋病毒、乙型肝炎和丙型肝炎病毒的单一感染及合并感染的危险因素。
Risk factors for monoinfections and coinfections with HIV, hepatitis B and hepatitis C viruses in northern Spanish prisoners.
作者信息
Pallás J, Fariñas-Alvarez C, Prieto D, Llorca J, Delgado-Rodríguez M
机构信息
Provincial Prison, Santander, Spain.
出版信息
Epidemiol Infect. 1999 Aug;123(1):95-102. doi: 10.1017/s0950268899002538.
A cross-sectional study was conducted in prisons of Cantabria (northern Spain) from June 1992 to December 1994. Inmates were asked to participate in a survey on prevalence and risk factors for monoinfections and coinfections with HIV, HBV and HCV. Crude and multiple odds ratios of risk factors were calculated (by polychotomous logistic regression). Prevalence of coinfections was higher than that of monoinfections. IDU risk factors were the main independent variables associated with monoinfections and coinfections with these agents. The strength of association increased with the degree of coinfection for IDU risk factors and penal status, e.g. duration of injecting drug use for more than 5 years yielded an adjusted OR ranging from 1.3 (95% CI: 0.4-5.1) for HBV monoinfection to 180 (95% CI: 61.0-540.0) for HIV-HBV-HCV coinfection. In comparison, sexual behaviours were less important than IDU risk factors.
1992年6月至1994年12月期间，在西班牙北部坎塔布里亚的监狱中开展了一项横断面研究。研究要求囚犯参与一项关于HIV、HBV和HCV单一感染及合并感染的患病率和危险因素的调查。计算了危险因素的粗比值比和多重比值比（通过多分类逻辑回归）。合并感染的患病率高于单一感染。注射吸毒危险因素是与这些病原体单一感染及合并感染相关的主要独立变量。注射吸毒危险因素和刑罚状况的关联强度随合并感染程度的增加而增强，例如，注射吸毒超过5年，调整后的比值比范围从HBV单一感染的1.3（95%可信区间：0.4 - 5.1）到HIV-HBV-HCV合并感染的180（95%可信区间：61.0 - 540.0）。相比之下，性行为不如注射吸毒危险因素重要。
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