Lundervold D A, Belwood M F, Craney J L, Poppen R
Department of Education Psychology, The University of Texas at El Paso, 79968, USA.
J Behav Ther Exp Psychiatry. 1999 Jun;30(2):119-35. doi: 10.1016/s0005-7916(99)00015-4.
The effects of behavioral relaxation training (BRT) for the treatment of moderate to severe essential tremor (ET) was evaluated with two older adults, ages 73 and 83, using a single-case design and statistical analysis. Measures included within-session clinician and self-rated tremor severity and disability in activities of daily living (ADL), EMG activity, and daily self-ratings of tremor severity and ADL disabilities. Following a brief 2-4 week baseline period BRT was conducted. Clinically significant reductions of 47-66% in within session clinical and self-rated tremor severity and daily self-ratings were obtained. Statistically significant changes in self- and clinician ratings occurred following BRT. In some cases, EMG activity also declined following intervention. Results at a seven week follow up were mixed and related to continued use of relaxation skills. While the cost ratio (medication: BRT) indicates that relaxation training is more expensive relative to standard medical intervention, cost-benefit to patients off sets the financial difference. Relaxation training may be an efficacious first step in a biobehavioral stepped care treatment model.
采用单病例设计和统计分析方法，对两名年龄分别为73岁和83岁的老年人进行了行为放松训练（BRT）治疗中度至重度特发性震颤（ET）的效果评估。测量指标包括治疗期间临床医生评定和自我评定的震颤严重程度、日常生活活动（ADL）中的残疾程度、肌电图（EMG）活动，以及每日震颤严重程度和ADL残疾的自我评定。在经历了为期2 - 4周的简短基线期后，进行了BRT。治疗期间临床和自我评定的震颤严重程度以及每日自我评定结果出现了47% - 66%的显著临床降低。BRT后，自我评定和临床医生评定出现了统计学上的显著变化。在某些情况下，干预后EMG活动也有所下降。七周随访结果不一，与放松技巧的持续使用有关。虽然成本比（药物治疗：BRT）表明，相对于标准医疗干预，放松训练成本更高，但对患者的成本效益抵消了经济差异。放松训练可能是生物行为阶梯式护理治疗模式中有效的第一步。
