Balle J, Olofsson M J, Hilden J
H:S Hvidovre Hospital, familieambulatoriet.
Ugeskr Laeger. 1999 Sep 6;161(36):5024-8.
In two Copenhagen University hospitals 12,885 pregnant women, seen during the period 1.8.1992 to 30.04.1995, answered questionnaires regarding consumption of alcohol, tobacco, cannabis and other drugs. The prevalence of cannabis use was 0.8%. Women using cannabis but no other illicit drugs were each retrospectively matched with four randomly chosen pregnant women in the same period and the same age group and with same parity. Eighty-four cannabis users were included. These women were socioeconomically disadvantaged and had a higher prevalence of present and past use of alcohol, tobacco and other drugs. No significant difference in pregnancy, delivery or puerperal outcome was found. Children of women using cannabis were 150 g lighter, 1.2 cm shorter and had 0.2 cm smaller head circumference than the control infants. Controlling for the child's sex and maternal use of alcohol did not eliminate the significant differences in birthweight and length; however, they were eliminated by controlling for maternal tobacco smoking. It is concluded, that the use of cannabis is not a major prognostic factor regarding the outcome of pregnancy, but is an indicator of low socioeconomic status and use of other substances.
在哥本哈根的两家大学医院，1992年8月1日至1995年4月30日期间就诊的12885名孕妇回答了关于酒精、烟草、大麻和其他药物使用情况的问卷。大麻使用的患病率为0.8%。使用大麻但不使用其他非法药物的女性，每人都与同期、同年龄组且 parity相同的四名随机选择的孕妇进行回顾性匹配。纳入了84名大麻使用者。这些女性在社会经济方面处于不利地位，目前和过去使用酒精、烟草和其他药物的患病率较高。在妊娠、分娩或产褥期结局方面未发现显著差异。使用大麻的女性所生子女比对照婴儿轻150克，矮1.2厘米，头围小0.2厘米。控制孩子的性别和母亲使用酒精并没有消除出生体重和身长的显著差异；然而，通过控制母亲吸烟，这些差异被消除了。得出的结论是，使用大麻不是妊娠结局的主要预后因素，但它是社会经济地位低下和使用其他物质的一个指标。
