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排序平均法——原理及其在听觉脑干反应中的应用

Sorted averaging--principle and application to auditory brainstem responses.

作者信息

Mühler R, von Specht H

机构信息

Department of Experimental Audiology and Medical Physics, Otto-von-Guericke-University Magdeburg, Germany.

出版信息

Scand Audiol. 1999;28(3):145-9. doi: 10.1080/010503999424716.

Abstract

A new averaging method for evoked potentials, called sorted averaging, is presented. The method requires an ensemble of sweeps stored in memory and is based on the principle of interchangeability of individual sweeps within this ensemble. Sorted averaging is applied by sorting all sweeps according to their estimated background noise and successive averaging of this sorted ensemble, starting with low-noise sweeps. Signal-to-noise power ratio (SNR2) is estimated by calculating the inverse single point variance (Elberling & Don, 1984). This SNR2 estimate increases linearly with the number of sweeps for standard averaging and shows a clear maximum for sorted averaging. Auditory brainstem responses to click stimuli at 70 dB nHL in 20 normal hearing subjects were recorded and 4000 individual sweeps during each run were stored for analysis. In an off-line analysis, SNR2 for standard averaging with 10 microV artefact rejection, for weighted averaging and for sorted averaging were calculated. Sorted averaging was found to yield a significantly higher SNR2.

摘要

本文介绍了一种新的诱发电位平均方法,称为排序平均法。该方法需要将一系列扫描存储在内存中,并基于该系列中各个扫描的可互换性原理。排序平均法的应用是先根据估计的背景噪声对所有扫描进行排序,然后从低噪声扫描开始对这个排序后的系列进行逐次平均。通过计算逆单点方差(埃尔伯林和唐,1984年)来估计信噪比(SNR2)。对于标准平均法,该SNR2估计值随扫描次数线性增加,而对于排序平均法则呈现出明显的最大值。记录了20名听力正常受试者在70 dB nHL时对点击刺激的听觉脑干反应,每次记录过程中存储4000个单独的扫描用于分析。在离线分析中,计算了具有10微伏伪迹剔除的标准平均法、加权平均法和排序平均法的SNR2。结果发现,排序平均法产生的SNR2显著更高。

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