1951年至1991年西班牙宫颈癌死亡率上升。
Increase in cervical cancer mortality in Spain, 1951-1991.
作者信息
Llorca J, Prieto M D, Delgado-Rodríguez M
机构信息
Division of Preventive Medicine and Public Health, School of Medicine, University of Cantabria, Santander, Spain.
出版信息
J Epidemiol Community Health. 1999 Jul;53(7):408-11. doi: 10.1136/jech.53.7.408.
BACKGROUND
The trend in cervical cancer mortality in Spain from 1951 to 1991 is examined.
METHODS
Analysis of national mortality statistics calculating age standardised mortality rates and an age-period cohort analysis. A fit to the Gompertz function was made to estimate the influence of the environmental factors on the mortality rates evolution.
MAIN RESULTS
The age standardised mortality rate in Spain is lower than in other developed countries (USA or Estonia) and equal to Norwegian and Finland rates; but whereas in these countries the trend is to decrease, the Spanish rate has increased during this period, because of a cohort effect. A misclassification bias could be responsible for the trend in women aged 40 and older but the increasing trend in younger women could not be interpreted as espurious. The Gompertzian analysis suggests an increase in environmental factors causing cervical cancer.
CONCLUSIONS
Cervical cancer mortality rates are increasing in Spain because of environmental factors.
背景
研究了1951年至1991年西班牙宫颈癌死亡率的趋势。
方法
分析国家死亡率统计数据，计算年龄标准化死亡率，并进行年龄-时期-队列分析。对冈珀茨函数进行拟合，以估计环境因素对死亡率演变的影响。
主要结果
西班牙的年龄标准化死亡率低于其他发达国家（美国或爱沙尼亚），与挪威和芬兰的死亡率相当；但在这些国家死亡率呈下降趋势，而在此期间西班牙的死亡率却因队列效应而上升。40岁及以上女性的这种趋势可能是由错误分类偏差导致的，但年轻女性死亡率上升的趋势不能解释为虚假的。冈珀茨分析表明，导致宫颈癌的环境因素有所增加。
结论
由于环境因素，西班牙的宫颈癌死亡率正在上升。
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