Aareleid T, Pukkala E, Thomson H, Hakama M
Department of Biostatistics and Epidemiology, Institute of Experimental and Clinical Medicine, Tallinn, Estonia.
Eur J Cancer. 1993;29A(5):745-9. doi: 10.1016/s0959-8049(05)80359-4.
Long term trends in the incidence of and mortality from invasive cervical cancer have been studied in Finland (1953-1987) and Estonia (1968-1987). The analyses are based on the data from the Finnish and Estonian Cancer Registries. An organised nationwide screening programme for cervical cancer was started in Finland in the early 1960s. In Estonia, no cytological screening programme has been introduced, and cervical malignancies are diagnosed in routine gynaecological practice. During 1968-1987, both the incidence of and mortality from cervical cancer were considerably higher in Estonia than in Finland. A decrease has taken place in the cervical cancer incidence and mortality in both countries since the mid-1960s, but whereas in Finland the decrease has been marked, in Estonia it has been less pronounced and levelled off in the 1980s. In 1987, the age-standardised (world population) incidence rate per 100,000 women was 14.0 in Estonia and 3.8 in Finland, and the age-standardised mortality rate was 6.0 and 1.6 per 100,000, respectively. The difference in the incidence of the disease in the two neighbouring countries can be partially attributed to socioeconomic factors. The main reason for the different slopes of the trend curves for cervical cancer is probably the difference in public health policies: an effective mass screening programme is being conducted in Finland but not in Estonia.
芬兰(1953 - 1987年)和爱沙尼亚(1968 - 1987年)对浸润性宫颈癌的发病率和死亡率的长期趋势进行了研究。分析基于芬兰和爱沙尼亚癌症登记处的数据。芬兰在20世纪60年代初启动了一项全国性的宫颈癌有组织筛查计划。在爱沙尼亚,尚未推行细胞学筛查计划,宫颈癌在常规妇科诊疗中被诊断出来。1968 - 1987年期间,爱沙尼亚宫颈癌的发病率和死亡率均显著高于芬兰。自20世纪60年代中期以来,两国宫颈癌的发病率和死亡率均有所下降,但芬兰的下降幅度显著,而爱沙尼亚的下降幅度较小,并在20世纪80年代趋于平稳。1987年,爱沙尼亚每10万名女性的年龄标准化(世界人口)发病率为14.0,芬兰为3.8;年龄标准化死亡率分别为每10万6.0和1.6。这两个邻国疾病发病率的差异部分可归因于社会经济因素。宫颈癌趋势曲线斜率不同的主要原因可能是公共卫生政策的差异:芬兰正在开展有效的大规模筛查计划,而爱沙尼亚则没有。