Holm C, Christensen M, Schulze S, Rosenberg J
Department of Surgical Gastroenterology 235, Hvidovre University Hospital, Denmark.
Eur J Surg. 1999 Aug;165(8):755-8. doi: 10.1080/11024159950189537.
To evaluate the effect of supplementary oxygen on heart rate and arterial oxygen saturation during colonoscopy.
Controlled study.
Two university hospitals, Denmark.
40 patients having colonoscopy.
20 patients were given supplementary oxygen through nasal prongs (2 L/min), and 20 patients breathed room air during colonoscopy. All patients were given conscious sedation and were monitored with a pulse oximeter during colonoscopy.
Tachycardia (pulse rate>100 min(-1)) and arterial oxygen desaturation (SpO2<90%) during colonoscopy.
There were no differences in the incidence of tachycardia or mean heart rate during endoscopy between the two groups, and no patient developed symptomatic cardiac arrhythmias or hypotensive episodes. 10 patients in the room air compared with none in the oxygen treatment group (p = 0.0004) had one or more episodes during which arterial oxygen saturation fell below 90% during colonoscopy, and mean oxygen saturation was higher in the oxygen treatment group than in the room air group (p < 0.001). No clinical complications occurred in either group.
Hypoxaemia and tachycardia are common during routine colonoscopy. The use of supplemental oxygen prevented hypoxaemia, but had no significant effect on heart rate.
评估结肠镜检查期间补充氧气对心率和动脉血氧饱和度的影响。
对照研究。
丹麦的两家大学医院。
40例行结肠镜检查的患者。
20例患者通过鼻导管接受补充氧气（2升/分钟），20例患者在结肠镜检查期间呼吸室内空气。所有患者均接受清醒镇静，并在结肠镜检查期间用脉搏血氧仪进行监测。
结肠镜检查期间的心动过速（脉搏率>100次/分钟）和动脉血氧饱和度下降（SpO2<90%）。
两组在内镜检查期间心动过速的发生率或平均心率无差异，且无患者发生有症状的心律失常或低血压发作。呼吸室内空气组有10例患者在结肠镜检查期间出现一次或多次动脉血氧饱和度低于90%的情况，而氧气治疗组无此情况（p = 0.0004），且氧气治疗组的平均血氧饱和度高于呼吸室内空气组（p < 0.001）。两组均未发生临床并发症。
常规结肠镜检查期间低氧血症和心动过速很常见。补充氧气可预防低氧血症，但对心率无显著影响。
