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[用溶链菌制剂行化学性胸膜固定术成功治疗肺癌合并乳糜胸]

[Lung cancer with chylothorax successfully treated by chemical pleurodesis with OK-432].

作者信息

Koga Y, Mita Y, Dobashi K, Masuo T, Aihara M, Shimizu Y, Umegae Y, Mori M

机构信息

Department of Internal Medicine, Public Tomioka General Hospital, Gunma, Japan.

出版信息

Nihon Kokyuki Gakkai Zasshi. 1999 Aug;37(8):627-30.

Abstract

A 66-year-old man was admitted to our hospital because of bloody sputum. Chest computed tomographic scans disclosed a right hilar tumor. A tumor in the right upper-lobe bronchus was detected by fiberoptic bronchoscopy. Microscopic examination disclosed moderately differentiated squamous cell carcinoma. The patient was treated with irradiation and combination chemotherapy. Thereafter, right chylous pleural effusion developed and continued to accumulate. Pleurodesis was induced by the intrathoracic injection of OK-432 at 15 KE per dose. Lung cancer with nontraumatic chylothorax is rare. In our patient, pleurodesis with OK-432 was an effective treatment.

摘要

一名66岁男性因咯血痰入院。胸部计算机断层扫描显示右肺门肿瘤。经纤维支气管镜检查发现右上叶支气管肿瘤。显微镜检查显示为中分化鳞状细胞癌。患者接受了放疗和联合化疗。此后,出现右侧乳糜胸并持续积液。通过胸腔内注射OK-432,每剂15KE进行胸膜固定术。非创伤性乳糜胸的肺癌罕见。在我们的患者中,OK-432胸膜固定术是一种有效的治疗方法。

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