Grobmyer S R, Guillem J G, O'Riordain D S, Woodruff J M, Shriver C, Brennan M F
Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.
Dis Colon Rectum. 1999 Sep;42(9):1216-9. doi: 10.1007/BF02238578.
Multiple endocrine neoplasia type 2B is best known for its endocrine manifestations and typical phenotype. The gastrointestinal manifestations, however, are also an important and commonly unrecognized component of the syndrome. We present four cases that demonstrate the varied presentation of patients with colonic manifestations of multiple endocrine neoplasia type 2B. We discuss the cause, diagnostic significance, and management of the colonic disease that is a component of multiple endocrine neoplasia type 2B.
2B型多发性内分泌腺瘤病以其内分泌表现和典型表型最为人所知。然而,胃肠道表现也是该综合征的一个重要且常未被认识到的组成部分。我们报告了4例病例,这些病例展示了2B型多发性内分泌腺瘤病结肠表现患者的不同表现形式。我们讨论了作为2B型多发性内分泌腺瘤病一部分的结肠疾病的病因、诊断意义及治疗。