一些N-苯磺酰基苯并咪唑的合成与抗病毒活性
Synthesis and antiviral activity of some N-benzenesulphonylbenzimidazoles.
作者信息
Garuti L, Roberti M, Cermelli C
机构信息
Department of Pharmaceutical Science, University of Bologna.
出版信息
Bioorg Med Chem Lett. 1999 Sep 6;9(17):2525-30. doi: 10.1016/s0960-894x(99)00429-1.
Abstract
Some N-sulphonylated benzimidazoles were synthesized as potential antiviral agents. Compound 16b and, to a lesser extent, 19b showed activity against two RNA viruses at micromolar concentrations.
摘要
合成了一些N-磺酰化苯并咪唑作为潜在的抗病毒剂。化合物16b以及在较小程度上的19b在微摩尔浓度下对两种RNA病毒显示出活性。
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