Chou T D, Gibran N S, Urdahl K, Lin E Y, Heimbach D M, Engrav L H
Department of Surgery, Tri-Service General Hospital, Taipei, Taiwan.
Burns. 1999 Sep;25(6):549-52. doi: 10.1016/s0305-4179(99)00031-5.
Methemoglobinemia is a rare complication in individuals exposed to nitrates or nitrites. Whereas methemoglobinemia is a recognized potential complication in burn patients treated with topical 0.5% silver nitrate solution, no report of methemoglobinemia in burn patients has been present in the literature for more than 15 years. We raise consciousness about this complication with a case report of a 12-month-old child with necrotizing fasciitis resulting from a cutaneous flank infection. The patient developed cyanosis 20 days after initiation of topical treatment with 0.5% silver nitrate solution. Intravenous injection of methylene blue can restore normal blood oxygenation.
高铁血红蛋白血症是接触硝酸盐或亚硝酸盐的个体中罕见的并发症。虽然高铁血红蛋白血症是在用0.5%硝酸银溶液局部治疗的烧伤患者中公认的潜在并发症，但15多年来文献中一直没有关于烧伤患者发生高铁血红蛋白血症的报告。我们通过一例因侧腹皮肤感染导致坏死性筋膜炎的12个月大儿童的病例报告，提高对这种并发症的认识。患者在用0.5%硝酸银溶液开始局部治疗20天后出现发绀。静脉注射亚甲蓝可恢复正常的血液氧合。
