Friedman M, Tanyeri H, Landsberg R, Caldarelli D
Department of Head and Neck Surgery, Illinois Masonic Medical Center, USA.
Laryngoscope. 1999 Sep;109(9):1442-5. doi: 10.1097/00005537-199909000-00016.
OBJECTIVE/HYPOTHESIS: Turbinate medialization techniques have gained popularity in an attempt to prevent turbinate lateralization. Theoretically, adhesions between the septum and middle turbinate will prevent lateralization but may compromise airflow to the olfactory neuroepithelium and affect the sense of smell. No studies have addressed this issue. The objective of this study is to evaluate effects of middle turbinate medialization on olfaction.
A prospective controlled study of olfaction before and after middle turbinate medialization using the University of Pennsylvania Smell Identification Test (UP-SIT) and patient questionnaires.
Fifty patients underwent endoscopic sinus surgery (ESS) with middle turbinate medialization and preservation. The caudal end of the middle turbinate and the opposing septal mucosa were abraded with a microdebrider for iatrogenic synechia formation in an attempt to avoid lateralization of the middle turbinate. Each of the patients underwent preoperative assessment with a questionnaire and UPSIT. All patients were reevaluated approximately 5 weeks after surgery by endoscopic examination, questionnaire, and the UPSIT. The preoperative and postoperative questionnaire responses were compared for subjective analysis. Objectively, the preoperative and postoperative UPSIT scores were compared using the Student t test.
The questionnaires showed that the study population's subjective sense of smell either did not change or improved compared with the preoperative state. Objectively, there was a mean increase of UPSIT scores after surgery. This difference was not statistically significant (P = .4).
Middle turbinate medialization has no detectable adverse effect on olfaction.
目的/假设:鼻甲内移技术在预防鼻甲外移方面日益受到欢迎。从理论上讲,鼻中隔与中鼻甲之间的粘连可防止鼻甲外移,但可能会影响嗅觉神经上皮的气流,进而影响嗅觉。尚无研究探讨过此问题。本研究的目的是评估中鼻甲内移对嗅觉的影响。
一项前瞻性对照研究,采用宾夕法尼亚大学嗅觉识别测试(UP-SIT)和患者问卷,对中鼻甲内移前后的嗅觉进行评估。
50例患者接受了内镜鼻窦手术(ESS),术中进行中鼻甲内移并予以保留。用微型切割器对中鼻甲尾端及相对的鼻中隔黏膜进行擦伤处理,以形成医源性粘连,从而避免中鼻甲外移。每位患者术前均通过问卷和UP-SIT进行评估。所有患者在术后约5周通过内镜检查、问卷和UP-SIT进行重新评估。比较术前和术后问卷的回答以进行主观分析。客观上,使用学生t检验比较术前和术后的UP-SIT评分。
问卷显示,与术前状态相比,研究人群的主观嗅觉未发生变化或有所改善。客观上,术后UP-SIT评分平均有所提高。但这种差异无统计学意义(P = 0.4)。
中鼻甲内移对嗅觉无明显不良影响。