Lethimonnier F, Furber A, Morel O, Geslin P, L'Hoste P, Tadei A, Jallet P, Caron-Poitreau C, Le Jeune J J
Department of Nuclear Medicine, University Hospital of Angers, France.
Magn Reson Imaging. 1999 Oct;17(8):1111-20. doi: 10.1016/s0730-725x(99)00065-x.
Respiratory gating with navigator echo is a recent technique to detect diaphragm position in 3D magnetic resonance (MR) coronary angiography. The purpose of our study was to image proximal coronary arteries and to detect significant stenoses in patients with coronary artery diseases and to compare with contrast enhanced angiography results. Twenty patients with coronary artery diseases who were referred for conventional angiography underwent magnetic resonance angiography (MRA). Three-dimensional gradient echo volumes were acquired using cardiac and respiratory gating and fat suppression. Using reformatted oblique planes and maximum intensity projection technique, visualization coronary segments and detection of significant coronary stenoses were made. Eighty-three coronary segments were analyzed. The sensitivity and specificity were 65% and 93%, respectively. The corresponding positive and negative predictive values were 69% and 91%. This study shows the ability to image correctly coronary arteries and to identify proximal stenoses, but image quality need to be improved for an efficiency detection of coronary artery stenoses in clinical practice.
利用导航回波进行呼吸门控是一种在三维磁共振（MR）冠状动脉造影中检测膈肌位置的最新技术。我们研究的目的是对冠状动脉疾病患者的近端冠状动脉进行成像，检测明显狭窄，并与对比增强血管造影结果进行比较。20例因常规血管造影而转诊的冠状动脉疾病患者接受了磁共振血管造影（MRA）。使用心脏和呼吸门控以及脂肪抑制技术采集三维梯度回波容积数据。利用重组斜平面和最大强度投影技术，对冠状动脉节段进行可视化并检测明显的冠状动脉狭窄。共分析了83个冠状动脉节段。敏感性和特异性分别为65%和93%。相应的阳性和阴性预测值分别为69%和91%。本研究表明能够正确地对冠状动脉进行成像并识别近端狭窄，但在临床实践中，为了有效检测冠状动脉狭窄，图像质量仍需提高。
