Sher A E
Capital Region Sleep/Wake Disorders Center, Capital Region Otolaryngology-Head and Neck Group, Albany (NY) Medical College, USA.
Ear Nose Throat J. 1999 Sep;78(9):694-5, 698-700, 703-6 passim.
Sleep disordered breathing was first described in ancient times. It is the result of a three-way interaction between the sleep/wake state-specific mechanisms of respiratory control, the interfacing of these mechanisms during times of state change, and the physical properties of the head and neck. Sleep disordered breathing results in pathological daytime sleepiness and is associated with significant cardiovascular morbidity. This paper reviews the history of the field, the physiologic and structural factors that result in sleep disordered breathing, and the implications of these factors for therapy.
睡眠呼吸障碍在古代就首次被描述。它是呼吸控制的睡眠/觉醒状态特异性机制、这些机制在状态变化时的相互作用以及头颈部物理特性之间三方相互作用的结果。睡眠呼吸障碍会导致病理性日间嗜睡,并与显著的心血管疾病发病率相关。本文回顾了该领域的历史、导致睡眠呼吸障碍的生理和结构因素,以及这些因素对治疗的影响。