Solon F S, Fernandez T L, Latham M C, Popkin B M
J Am Diet Assoc. 1979 Feb;74(2):112-8.
In a three-year pilot project in the Philippines, the magnitude of vitamin A deficiency and its clinical manifestation (xerophthalmia) was determined, and three alternate programs for eliminating and preventing it in various ecologic zones were designed and implemented concurrently in separate areas in each ecologic zone. Results were evaluated, and costs and benefits of each program were determined. The results of the fortification program are reported. Monosodium glutamate (MSG) was selected as the ideal carrier was fortified at a level which provided 15,000 I.U. retinol palmitate to the average family each day. Significant increases in serum A, especially for children with more deficient vitamin A status, resulted. The program's economic benefits significantly outweighted the costs, and the MSG fortification program has been expanded to several additional pilot provinces in the Philippines.
在菲律宾开展的一个为期三年的试点项目中,测定了维生素A缺乏症的严重程度及其临床表现(干眼病),并在每个生态区域的不同地区同时设计并实施了三个在不同生态区域消除和预防该病症的替代方案。对结果进行了评估,并确定了每个方案的成本和效益。报告了强化方案的结果。选择味精(MSG)作为理想载体,以每天为普通家庭提供15,000国际单位视黄醇棕榈酸酯的水平进行强化。血清A显著增加,尤其是维生素A状况更缺乏的儿童。该方案的经济效益明显超过成本,味精强化方案已扩展到菲律宾的其他几个试点省份。