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正常对照人群中种族与睡眠模式的关系:对精神病理学及治疗的启示

Relationship between ethnicity and sleep patterns in normal controls: implications for psychopathology and treatment.

作者信息

Rao U, Poland R E, Lutchmansingh P, Ott G E, McCracken J T, Lin K M

机构信息

Department of Psychiatry, Harbor-UCLA Medical Center, Torrance, CA, USA.

出版信息

J Psychiatr Res. 1999 Sep-Oct;33(5):419-26. doi: 10.1016/s0022-3956(99)00019-9.

DOI:10.1016/s0022-3956(99)00019-9
PMID:10504010
Abstract

The purpose of the study was to examine ethnic influences on sleep regulation. Seventy-three normal volunteers from four ethnic groups (17 African-Americans, 10 Asians, 30 Caucasians and 16 Hispanics) were studied for two consecutive nights with sleep polysomnography recordings in the laboratory. The subjects were in good physical and psychological health, and were asymptomatic with respect to sleep/wake complaints or sleep disorders. With the exception of minor differences, sleep continuity, sleep architecture and rapid eye movement (REM) sleep patterns were comparable among the four groups. African-Americans had evidence of more stages 1 and 2 and diminished stage 4 sleep, whereas the Hispanics had higher REM density. These preliminary findings suggest that sleep patterns are remarkably similar across cultures. There are, however, important cross-ethnic differences, specifically in the depth of sleep and in phasic REM measures. Because sleep disturbances are common symptoms of emotional disorders and since many psychoactive agents affect sleep, cross-ethnic differences in sleep patterns may have potential implications for the treatment and prevention of psychiatric disorders.

摘要

该研究的目的是检验种族对睡眠调节的影响。来自四个种族群体的73名正常志愿者(17名非裔美国人、10名亚洲人、30名白种人和16名西班牙裔)在实验室连续两晚接受睡眠多导睡眠图记录研究。研究对象身体健康、心理状态良好,无睡眠/觉醒方面的主诉或睡眠障碍症状。除了细微差异外,四组之间的睡眠连续性、睡眠结构和快速眼动(REM)睡眠模式具有可比性。非裔美国人有更多1期和2期睡眠的证据,4期睡眠减少,而西班牙裔有更高的REM密度。这些初步研究结果表明,睡眠模式在不同文化中非常相似。然而,存在重要的跨种族差异,特别是在睡眠深度和REM阶段测量方面。由于睡眠障碍是情绪障碍的常见症状,并且许多精神活性药物会影响睡眠,睡眠模式的跨种族差异可能对精神疾病的治疗和预防具有潜在影响。

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