Salvesen K A, Dahlø R, Sommer T, Bevanger L
Kvinneklinikken, Regionsykehuset i Trondheim.
Tidsskr Nor Laegeforen. 1999 Aug 30;119(20):2990-2.
Prenatal screening for group B streptococcus colonisation in pregnant women is controversial, though recommended in some countries. We aimed to compare the detection rate when pregnant women performed their own vaginal/anorectal swabs with the standard practice of physician obtained swabs. During six months, 89 pregnant women with high risk for premature labor collected their own vaginal/anorectal swab after instruction from a midwife. Afterwards a physician took a similar sample among 80 of the women. All together, 30 (34%) out of 89 women were carriers of group B streptococcus. Comparing the efficacy of the sampling procedures among 80 women who had taken both tests, we found that 25 of 26 positive cultures were identified by self-collected samples, while 17 out of 26 were identified by samples collected by the physicians. The difference in sensitivity (96% vs 65%) was statistically significant (p < 0.001) with a kappa value of 0.68. Self-collected vaginal/anorectal swabs for the identification of group B streptococcus carriers are at least as sensitive as the practice of physician performed swabs.
孕妇B族链球菌定植的产前筛查存在争议，尽管在一些国家是推荐进行的。我们旨在比较孕妇自行采集阴道/直肠拭子与医生按标准操作采集拭子的检测率。在六个月期间，89名有早产高风险的孕妇在助产士指导下自行采集阴道/直肠拭子。之后，一名医生在其中80名女性中采集了类似样本。总共，89名女性中有30名（34%）是B族链球菌携带者。比较80名接受了两种检测的女性中采样程序的效果，我们发现26份阳性培养物中有25份通过自行采集的样本检测出来，而26份中有17份通过医生采集的样本检测出来。敏感性差异（96%对65%）具有统计学意义（p < 0.001），kappa值为0.68。自行采集阴道/直肠拭子用于识别B族链球菌携带者至少与医生采集拭子的做法一样敏感。
