Smith R F, Rutt B K, Holdsworth D W
Imaging Research Laboratories, The John P. Robarts Research Institute, London, Ontario, Canada.
J Magn Reson Imaging. 1999 Oct;10(4):533-44. doi: 10.1002/(sici)1522-2586(199910)10:4<533::aid-jmri6>3.0.co;2-z.
Anthropomorphic carotid bifurcation flow phantoms that incorporate different stenotic geometries within the internal carotid artery have been developed. This technique produces high-fidelity, life-size vascular flow models that are compatible with magnetic resonance techniques. The models, in conjunction with a computer-controlled flow pump, address the need for a complex vascular geometry that can be used to verify magnetic resonance angiography (MRA) techniques that quantify stenosis severity and blood flow. Stenotic geometries, with up to 80% diameter reduction, have been fabricated in two different phantom materials. Plastic phantoms provide a durable, rigid geometry where the absolute dimensions of the model are well known. Agar gel phantoms provide tissue-like signal (T1, T2) up to the lumen boundary and are also compatible with ultrasound techniques. In this paper the technique to produce vascular flow phantoms is outlined and the compatibility of these phantoms with MRA techniques is demonstrated. J. Magn. Reson. Imaging 1999;10:533-544.
已经开发出了在颈内动脉内纳入不同狭窄几何形状的拟人化颈动脉分叉血流模型。该技术可产生与磁共振技术兼容的高保真、真人大小的血管血流模型。这些模型与计算机控制的血流泵相结合，满足了对可用于验证定量狭窄严重程度和血流的磁共振血管造影（MRA）技术的复杂血管几何形状的需求。已经用两种不同的模型材料制作了直径减少高达80%的狭窄几何形状。塑料模型提供了一种耐用、刚性的几何形状，其中模型的绝对尺寸是众所周知的。琼脂凝胶模型在管腔边界处提供类似组织的信号（T1、T2），并且也与超声技术兼容。本文概述了制作血管血流模型的技术，并展示了这些模型与MRA技术的兼容性。《磁共振成像杂志》1999年；10：533 - 544。
