Bejsovec A
Northwestern University Department of Biochemistry, Molecular Biology and Cell Biology 2153 Sheridan Road, Evanston, Illinois 60208, USA.
Curr Biol. 1999 Sep 23;9(18):R684-7. doi: 10.1016/s0960-9822(99)80439-4.
Wnt signalling controls many different cell fate choices in a wide variety of animal species. Recent studies have revealed that regulatory interactions at several steps in the pathway can modify its outcome, helping to explain how the same pathway can, in different contexts, have very different characteristics and consequences.
Wnt信号通路在多种动物物种中控制着许多不同的细胞命运选择。最近的研究表明,该信号通路中几个步骤的调控相互作用可以改变其结果,这有助于解释为何同一信号通路在不同情况下会具有非常不同的特征和后果。