Imperiali B, Ottesen J J
Deapartment of Chemistry, Massachusetts, Institute of Technology, Cambridge 02139, USA.
J Pept Res. 1999 Sep;54(3):177-84. doi: 10.1034/j.1399-3011.1999.00121.x.
Mini-proteins containing fewer than 40 amino acids provide simple model systems for studying protein folding and stability as well as serving as scaffolds for the rational design of new functional motifs. This article reviews current progress on the design and characterization of discretely folded mini-protein motifs.
包含少于40个氨基酸的微型蛋白质为研究蛋白质折叠和稳定性提供了简单的模型系统,同时也作为合理设计新功能基序的支架。本文综述了离散折叠微型蛋白质基序设计与表征的当前进展。