Alleva D Q, Smetherman D H, Farr G H, Cederbom G J
Department of Radiology, Ochsner Clinic, New Orleans, LA 70121, USA.
Radiographics. 1999 Oct;19 Spec No:S27-35; discussion S36-7. doi: 10.1148/radiographics.19.suppl_1.g99oc05s27.
Twenty-two cases were reviewed in which the diagnosis of radial scar (complex sclerosing lesion) of the breast was suspected preoperatively. At mammography, the lesions had a "black star" appearance with long, thin spicules radiating from a radiolucent central area. Excisional rather than core needle biopsy was recommended in all cases. In 13 of 22 cases, including one case of atypical ductal hyperplasia, the lesions proved benign at pathologic analysis. The remaining nine cases were malignant and included one case with a low-nuclear-grade cribriform and micropapillary ductal carcinoma in situ adjacent to the lesion. Results of this study confirm the previously reported association of atypical ductal hyperplasia and carcinoma with radial scar. Furthermore, they demonstrate that a mammographic finding suggestive of radial scar may represent a malignancy that mimics the typical imaging findings in these entities. In cases of mammographically suspected radial scar, all members of the management team as well as the patient should be made aware preoperatively of the potential for benign as well as malignant pathologic findings.
回顾了22例术前怀疑为乳腺放射状瘢痕(复杂性硬化性病变)的病例。在乳腺钼靶检查中,病变呈“黑星”状,有从透亮中心区域放射状伸出的细长毛刺。所有病例均建议行切除活检而非粗针穿刺活检。22例中的13例,包括1例非典型导管增生,病理分析显示病变为良性。其余9例为恶性,其中1例为低核级筛状和微乳头导管原位癌,与病变相邻。本研究结果证实了先前报道的非典型导管增生和癌与放射状瘢痕的关联。此外,研究表明,乳腺钼靶检查中提示放射状瘢痕的表现可能代表一种模仿这些实体典型影像学表现的恶性肿瘤。在乳腺钼靶检查怀疑为放射状瘢痕的病例中,术前应让管理团队的所有成员以及患者都了解良性和恶性病理结果的可能性。