Wacha D S
Med J Zambia. 1976;10(6):157-9.
A total of twenty eight patients living in a around the City of Lusaka, Zambia were subjected to a drug trial to determine the effect of a single oral dose of Tinidazole (Fasigyn Pfizer) in the treatment of Trichomonal Vaginitis. All the twenty eight patients were proven cases of Trichomonal Vaginitis from microscopy of cervical smears. Two grammes of Fasigyn were used as a single oral dose with yeast as Placebo. Twenty patients were originally treated with Fasigyn and eight received yeast. However two patients in the Fasigyn group absconded, but one later reported satisfactory results. The husbands of two others were untreated. Four patients had other vaginal infections. A microscopic cure rate of 100% and a corrected clinical cure rate of 93.3% was obtained using fasigyn. The side effects were minimal and the patients themselves regarded them as mild.
共有28名居住在赞比亚卢萨卡市周边的患者接受了一项药物试验，以确定单次口服替硝唑（法西加，辉瑞制药）治疗滴虫性阴道炎的效果。所有28名患者均通过宫颈涂片显微镜检查确诊为滴虫性阴道炎。将两克法西加作为单次口服剂量，以酵母作为安慰剂。最初20名患者接受法西加治疗，8名患者接受酵母治疗。然而，法西加组有两名患者潜逃，但其中一名后来报告效果良好。另外两名患者的丈夫未接受治疗。四名患者有其他阴道感染。使用法西加获得了100%的显微镜治愈率和93.3%的校正临床治愈率。副作用极小，患者自身认为副作用轻微。
